Browse our Research Articles

Page 3 of 1,367
    1. Microbiology and Infectious Disease

    FtsK is critical for the assembly of the unique divisome complex of the FtsZ-less Chlamydia trachomatis

    McKenna Harpring, Junghoon Lee ... John V Cox
    The novel divisome complex of Chlamydia trachomatis contains elements of the divisome and elongasome from other bacteria, and it requires the chromosomal translocase, FtsK, for its assembly.
    1. Neuroscience

    Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Julieta Gomez-Frittelli, Gabrielle Frederique Devienne ... Julia A Kaltschmidt
    Cadherin-6 (Cdh6) marks gut-intrinsic sensory neurons, and optogenetic activation of Cdh6+ sensory neurons is sufficient to evoke colonic motor complexes.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    SAM transmethylation pathway and adenosine recycling to ATP are essential for systemic regulation and immune response

    Pavla Nedbalová, Nikola Kaislerova ... Tomáš Doležal
    Adenosine produced by transmethylation may act as a sensor of the balance between cell activity and nutrient supply.
    1. Cancer Biology
    2. Cell Biology

    N6-methyladenosine in DNA promotes genome stability

    Brooke A Conti, Leo Novikov ... Mariano Oppikofer
    Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.
    1. Immunology and Inflammation

    CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

    Xiaoyu Meng, Yezhang Zhu ... Lie Wang
    CXXC1 is a pivotal epigenetic regulator that ensures Treg homeostasis and suppressive function by interacting with FOXP3 to modulate H3K4me3 deposition at key signature genes.
    1. Plant Biology

    The rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in Lotus japonicus

    Hanbin Bao, Yanan Wang ... Yangrong Cao
    The rhizobial effector NopT and two Nod factor receptors of Lotus japonicus, NFR1 and NFR5, mutually interact to precisely regulate rhizobial symbiosis.
    1. Developmental Biology

    Mesenchymal Meis2 controls whisker development independently from trigeminal sensory innervation

    Mehmet Mahsum Kaplan, Erika Hudacova ... Ondrej Machon
    Meis2 transcription factor instructs the mesenchyme to initiate whisker formation in the epithelium.
    1. Cell Biology

    Small-molecule activation of TFEB alleviates Niemann–Pick disease type C via promoting lysosomal exocytosis and biogenesis

    Kaili Du, Hongyu Chen ... Dan Li
    Small-molecule agonists of transcription factor EB alleviate Niemann–Pick disease type C via promoting lysosomal function.
    1. Neuroscience
    2. Physics of Living Systems

    Annihilation of action potentials induces electrical coupling between neurons

    Moritz Schloetter, Georg U Maret, Christoph J Kleineidam
    Action potentials of neurons expel a charge when they reach the axon terminal, and classical electrodynamics predict the resulting electric fields and its influence to other neurons by ephaptic coupling.
    1. Microbiology and Infectious Disease

    Linalool combats Saprolegnia parasitica infections through direct killing of microbes and modulation of host immune system

    Tao Tang, Weiming Zhong ... Zhipeng Gao
    Linalool demonstrates dual antimicrobial and immunomodulatory actions against Saprolegnia parasitica.