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A predominant but less studied sensory pathway for both vibrissa self-motion and touch inputs is shown to broadcast broadly to brainstem regions involved in regulation of autonomic functions as well as forebrain regions involved in expression of emotional reactions.

During an individual's lifetime, their brain undergoes a unique transformation that we have precisely mapped across thousands of people to create and share reference growth charts of the human brain's lifespan which allow for single subject exploration and inference.

Short linear motifs throughout the intrinsically disordered proteome use sequence context in diverse ways to target actin remodeler ENAH.

An in silico analysis of gap junction proteins supports the hypothesis that connexins replaced the primordial innexins in chordate gap junctions due to an evolutionary bottleneck.

Genome sequencing analysis dissects the origins and evolution of cancer transmission between clam species in the Seas of Southern Europe.

Optimising the use of transcriptomics enables screening of thousands of compounds and illustrates an approach that yields quantitative pharmacology at the single-gene and pathway level.

Increased catalysis has been suggested to be an adaptive trait of enzymes to growth at lower temperature, but systematic analysis suggests that temperature exerts a weak selection pressure on enzyme rate enhancement, with observed variation arising from other evolutionary forces.

In depth phenotyping from tissues and in vitro activation studies reveal antiviral function of MAIT cells- with particular emphasis on HIV infection.

Aging is associated with mitochondrial and cytosolic iron accumulation in the brain, which is through increased local expression of hepcidin, and subsequent iron accumulation due to decreased iron export through ferroportin-1.

Ruby-throated hummingbirds switch from using torpor to survive nighttime energy emergencies in the breeding season to using it to spare fat stores and gain premigratory mass in the late summer.