Browse our latest Chromosomes and Gene Expression articles

voyAGEr is an online platform that facilitates the exploration of age-related gene expression dynamics in human tissues, allowing users to analyse tissue- and sex-specific changes alongside donor medical histories.

Endothelial cell subpopulations are characterized by unique gene expression profiles, epigenetic landscapes and functional properties.

Imaging analysis confirms ChIP-Seq data on the distinct genomic distribution of histone H1 variants in AT-rich, nuclear peripheral regions (H1.2, H1.3, H1.5, H1.0) or GC-rich, throughout the nucleus (H1.4, H1X).

Single-particle imaging of RSC and ISW2 chromatin remodelers on DNA stretched between dual optical tweezers reveals distinctive 1D diffusion and opposing push–pull nucleosome translocation on engagement with sparse nucleosome arrays.

A technique called mSTARR-seq sheds light on how DNA methylation may shape responses to external stimuli by altering the activity of sequences that control gene expression.

To find nucleosomes, chromatin remodelers slide and hop along DNA, and their direction of approach affects the direction that nucleosomes slide in.

The mammalian CPEB3 self-cleaving ribozyme modulates expression of the CPEB3 mRNA and protein, altering translation of plasticity-related proteins and hippocampus-dependent memory.

Investigation of how cells rewire their transcriptional programs during transition from mitotic to meiotic cell fate reveals a two-pronged mechanism for inactivating a key mitotic transcription factor.