Browse our latest Chromosomes and Gene Expression articles

Differentiation of mitotic errors occurring during late embryonic development from the well-characterized first division defects provides new insight into the mechanisms of Wolbachia-induced cytoplasmic incompatibility.

A designed system to track homologous recombination (HR) in vivo demonstrates the importance of chromosome organization in the induction of global mobility in response to double-strand breaks and characterizes the role of two types of global motility in HR.

Brain-specific inactivation of cohesin-STAG2 in the mouse causes myelination defects, thus implicating hypomyelination as a contributing factor to cohesinopathy and establishing oligodendrocytes as a cell system to probe the physiological function of cohesin-mediated genome folding.

The pentameric condensin II complex is equipped with a multilayered, self-regulatory mechanism that supports mitotic chromosome assembly.

A genetic approach indicates that increased active somatic transposon activity can decrease life span and affect some but not all hallmarks of aging.

Genomic imprinting in the bryophyte Marchantia polymorpha by Polycomb results in maternal dominance of embryonic gene expression.

UBX proteins reduce the ubiquitin threshold of mammalian p97-UFD1-NPL4.

In vitro single-particle tracking reveals that ATP binding increases the one-dimensional diffusion of yeast chromatin remodeler SWR1 on DNA stretched between optical tweezers and diffusion is confined by protein roadblocks and nucleosomes.

Examination of the changes in the transcription start site selection in TCL1-driven chronic lymphocytic leukemia and their impact on mRNA translation revealed a marked elevation of intra-genic cryptic promoters, which are predicted to generate multiple N-terminally truncated or modified proteins.

A critical analysis of recent single-cell transcriptomic studies of Drosophila blood cells confirms the extreme plasticity of the major phagocyte class, identifies a new class of blood cell, and suggests relationships to blood cells in other insects.