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Disruption of the intracellular vimentin network upon cellular stress results in enhanced cell surface vimentin on human osteoarthritic chondrocytes and might represent a novel membrane-associated marker of stress-induced premature senescence.

It may be possible to treat cardiac hypertrophy and injury by using drugs that inhibit a protein called SIRT2.

Guidelines are presented to help researchers comply with sex-inclusive research mandates while upholding high standards of rigor.

A common genetic variant in Black patients increases the risk of renal disease, which increases the risk of sepsis, but there is no direct association between the variant and sepsis.

SIRT2 has detrimental effects in the heart and plays a role in cardiac response to injury and the progression of cardiac hypertrophy, and targeting SIRT2 may provide a novel avenue for the treatment of cardiac hypertrophy and ischemic disease.

Inhibiting triglyceride storage in adipose tissue prevents obesity and improves metabolic health.

Essential advice for trainees when evaluating postgraduate physician scientist training programs.

Intermittent fasting orchestrates molecular shifts, yielding cardiovascular improvements, revealing novel cardioprotective mechanisms, and suggesting innovative pharmacological strategies for cardiovascular disease prevention and treatment.

Neutrophils are the predominant phagocytes that clear dead liver cells under normal physiological conditions.

Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.