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  1. Episode 97: February 2025

    In this episode we hear about opioid overdoses, a new technique for studying teamwork in animals, making the most of fMRI data, how childhood adversity blunts the fear response in later life, and the neuroscientists looking to link patterns of brain activity to specific thought processes - by performing brain scans on people as they watch movies.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Neurodegeneration: A role for RNA knots in Alzheimer’s disease

    Silvia Galli, Marco Di Antonio
    The buildup of knot-like RNA structures in brain cells may be the key to understanding how uncontrolled protein aggregation drives Alzheimer’s disease.
    Version of Record
    Insight
    1. Developmental Biology

    Morphogenesis: Fluid transport comes to the fore

    Yufei Wu, Sean X Sun
    Proteins that allow water to move in and out of cells help shape the development of new blood vessels.
    Version of Record
    Insight
    1. Developmental Biology
    2. Neuroscience

    Axon Guidance: Watching axons on the move

    Maria I Lazaro-Pena, Carlos A Diaz-Balzac
    The ligand Netrin mediates axon guidance through a combination of haptotaxis over short distances and chemotaxis over longer distances.
    Version of Record
    Insight
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Drug Discovery: How to exploit the recycling system of a cell

    Sasha L Evans, Bethany A Haynes ... Rivka L Isaacson
    Nature has inspired the design of improved inhibitors for cancer-causing proteins.
    Version of Record
    Insight
  2. Point of View: To be, or not to be, part-time in academia

    Sinead English, M Emília Santos ... Nina F Ockendon-Powell
    Part-time working can be beneficial for individual academics, and also for academia as a whole.
    1. Cell Biology

    Beta Cells: Opportunity makes a hub or a leader

    Marjan Slak Rupnik
    Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.
    Version of Record
    Insight
    1. Evolutionary Biology
    2. Neuroscience

    Vision: The inner workings of a miniature eye

    Gregor Belušič
    The first complete 3D reconstruction of the compound eye of a minute wasp species sheds light on the nuts and bolts of size reduction.
    Version of Record
    Insight
    1. Medicine

    Special Issue: Reproductive Health

    Edited by Wei Yan et al.
    Our latest Special Issue showcases research in reproductive biology and medicine.
    1. Developmental Biology

    Special Issue: Reproductive health

    Wei Yan
    The articles in this special issue highlight the diversity and complexity of research into reproductive health, including the need for a better understanding of the fundamental biology of reproduction and for new treatments for a range of reproductive disorders.