Targeting a methyltransferase

Latest research

1. 1. Biochemistry and Chemical Biology

   Coordinated regulation of chemotaxis and resistance to copper by CsoR in Pseudomonas putida

   Meina He, Yongxin Tao ... Wenli Chen
2. 1. Cell Biology

   Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction

   Jittoku Ihara, Yibin Huang ... Koichi Yamamoto
3. 1. Chromosomes and Gene Expression

   Srs2 binding to PCNA and its sumoylation contribute to RPA antagonism during the DNA damage response

   Jiayi Fan, Nalini Dhingra ... Xiaolan Zhao
4. 1. Biochemistry and Chemical Biology
   2. Developmental Biology

   Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control

   Mykola Roiuk, Marilena Neff, Aurelio A Teleman
5. 1. Structural Biology and Molecular Biophysics

   Wide Transition-State Ensemble as Key Component for Enzyme Catalysis

   Gabriel Ernesto Jara, Francesco Pontiggia ... Dorothee Kern
6. 1. Microbiology and Infectious Disease

   Wag31, a membrane tether, is crucial for lipid homeostasis in mycobacteria

   Yogita Kapoor, Himani Khurana ... Vinay Kumar Nandicoori
7. 1. Developmental Biology

   Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice

   Alexandra V Bruter, Ekaterina A Varlamova ... Victor V Tatarskiy
8. 1. Cell Biology
   2. Computational and Systems Biology

   Unbiased identification of cell identity in dense mixed neural cultures

   Sarah De Beuckeleer, Tim Van De Looverbosch ... Winnok H De Vos

   Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
9. 1. Neuroscience

   Prolactin-mediates a lactation-induced suppression of arcuate kisspeptin neuronal activity necessary for lactational infertility in mice

   Eleni Hackwell, Sharon R Ladyman ... David R Grattan

   Lactational infertility in mice is dependent on prolactin action in kisspeptin neurons.
10. 1. Neuroscience

    Realistic mossy fiber input patterns to unipolar brush cells evoke a continuum of temporal responses comprised of components mediated by different glutamate receptors

    Vincent Huson, Wade G Regehr

    Different glutamate receptors have specialized roles that allow cerebellar unipolar brush cells to transform realistic mossy fiber input patterns into a continuum of temporal responses.